GBA 抗体
Quick Overview for GBA 抗体 (ABIN7074062)
抗原
See all GBA 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 大鼠
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纯化方法
- Affinity purification
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免疫原
- KLH conjugated Synthetic peptide corresponding to Mouse GBA
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anti-Glucosidase, Beta, Acid (GBA) (AA 146-235) antibody
GBA 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-Glucosidase, Beta, Acid (GBA) (AA 117-214) antibodyGBA 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, Beta, Acid (GBA) (AA 334-498) antibodyGBA 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, Beta, Acid (GBA) antibodyGBA 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, Beta, Acid (GBA) (C-Term) antibodyGBA 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, Beta, Acid (GBA) (AA 255-509) antibodyGBA 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, Beta, Acid (GBA) (AA 215-343) antibodyGBA 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, Beta, Acid (GBA) (AA 1-536) antibodyGBA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Glucosidase, Beta, Acid (GBA) (AA 1-536) antibodyGBA 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glucosidase, Beta, Acid (GBA) (AA 146-235) antibodyGBA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H4 unconjugated
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应用备注
- IHC/IF (M,R) 1:1000-1:2000/1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- GBA (Glucosidase, Beta, Acid (GBA))
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别名
- GBA
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背景
- The GBA is a glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes . Through the production of ceramides, participates to the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism . May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol . The short chain saturated C8:0-GlcCer and the mono-unsaturated C18:0-GlcCer being the most effective glucose donors for that transglucosylation reaction. Under specific conditions, may alternatively catalyze the reverse reaction, transferring glucose from cholesteryl-beta-D-glucoside to ceramide. Finally, may also hydrolyze cholesteryl-beta-D-glucoside to produce D-glucose and cholesterol .
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基因ID
- 14466
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NCBI登录号
- NP_001070879
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UniProt
- P17439
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途径
- Cellular Glucan Metabolic Process
抗原
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